Genome Guardian Free Download (v4.1.0)

Game Overview

Dive into a microscopic alien world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that’s easy to pick up but hard to master. Research permanent upgrades to survive 70 different microbes across 8 game modes, each with multiple ascension levels (“depths”).

Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!

  • Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
  • Bomb + Bomb doubles down on explosive power to make Bazooka!
  • Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!
  • 49 Turrets with unique strengths and functions
  • 96 Perks to mix and match that drastically change how you play
  • 72 Turret & Weapon Mods that can turn shots into sticky mines or bouncing fireballs
  • 32 Mutations that alter the challenges you face each run
  • 20-minute Runs that can be continued in Endless Mode
  • 60 Bassy Electronic Tunes that adapt to the current mood and intensity
  • 100 Steam Achievements
  • 49 Cosmetics including spider legs, tank tread and a swarm of drones
  • Accessibility Settings for colourblindness and motion sickness
  • Cloud Save
  • Plays great on Steam Deck! (official Steam Deck Compatibility Review pending)

Genome Guardian is a product of passion – a culmination of everything I love about roguelite shooters, and a novel ‘weapon-combining’ feature that I’ve wanted to realize since I was a teenager. Your support will mean content updates and allow me to make more games in the future.

How to Download & Install Genome Guardian

  • Access the Link: Click the button below to go to Crolinks. Wait 5 seconds for the link to generate, then proceed to UploadHaven.
  • Start the Process: On the UploadHaven page, wait 15 seconds and then click the grey “Free Download” button.
  • Extract the Files: After the file finishes downloading, right-click the .zip file and select “Extract to Genome Guardian”. (You’ll need WinRAR for this step.)
  • Run the Game: Open the extracted folder, right-click the .exe file, and select “Run as Administrator.”
  • Enjoy: Always run the game as Administrator to prevent any saving issues.

 


Genome Guardian (v4.1.0)
Size: 487.51 MB

🎮 Mode | Single Player
🖥 Platform | Windows PC

FAQ – Frequently Asked Questions

  • Is this game cracked? Yes, this is a fully pre-installed version.
  • 🛡️ Is this safe to download? 100% safe—every game is checked before uploading.
  • 🍎 Can I play this on Mac? No, this version is only for Windows PC.
  • 🎮 Does this include DLCs? Some versions come with DLCs—check the title.
  • 💾 Why is my antivirus flagging it? Some games trigger false positives, but they are safe.

System Requirements

  • OS: Windows 10
  • Storage: 600 MB available space
  • Additional Notes: Turn down “Render Scale” in settings if framerate is low

Screenshots